compound 17 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T11942	MAP4K4-IN-3	Compound 17	MAPK
	MAP4K4-IN-3 (Compound 17) may be a viable target for antidiabetic agents, a serine/threonine protein kinase.		MAPK
T2884	Cortisone	Kendall's compound E,17-Hydroxy-11-dehydrocorticosterone	Glucocorticoid Receptor , Endogenous Metabolite
	Cortisone (17-Hydroxy-11-dehydrocorticosterone) is a corticosteroid with potent glucocorticoid activity.		Glucocorticoid Receptor , Endogenous Metabolite
T0948L	Corticosterone	17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,Corticosterone (From plants)	Glucocorticoid Receptor , Endogenous Metabolite
	Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active. Corticosterone is involved in the regulation of energy, immune responses, and stres...		Glucocorticoid Receptor , Endogenous Metabolite
T9191	XMD-17-51 Trifluoroacetate	XMD-17-51 Trifluoroacetate (1628614-50-5 free base)	AMPK
	XMD-17-51 Trifluoroacetate is a pyrimido-diazepinone compound that regulates protein kinases.		AMPK
T60440	Antiviral agent 17
	Antiviral agent 17 (Compound 4) is an anti-infection agent that retains its strong antiviral effect in a human replicon assay with an EC50 of 0.015 μM. Antiviral agent 17 shows good antiviral activity against murine noro...
T61589	C-Fms-IN-13		c-Fms
	c-Fms-IN-13 (compound 14) is a potent FMS kinase inhibitor (IC50= 17 nM). c-Fms-IN-13 is an anti-inflammatory agent.		c-Fms
TN1195	17-Hydroxy sprengerinin C		BCL , Others , Caspase
	17-Hydroxy sprengerinin C is a glycoside compound isolated from rhizomes of Polygonatum sibiricum with stronger anticancer activities. 17-Hydroxy sprengerinin C reduces the expression of Blc-2 and pro-caspase3 and increa...		BCL , Others , Caspase
T9218	Andrograpanin	19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE	p38 MAPK
	Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) is a bioactive compound from Andrographis paniculata. Andrograpanin has anti-inflammatory and anti-infectious properties.		p38 MAPK
TN2539	1beta-Hydroxyalantolactone		IL Receptor , TNF
	1beta-Hydroxyalantolactone is a small molecular compound isolated from the flower head of the medicinal plant giant British flower, which can inhibit the expression of TNF-α, IL-17 and IFN-γ in cells, promote the secreti...		IL Receptor , TNF
T60796	Cholesterol 24-hydroxylase-IN-1
	Cholesterol 24-hydroxylase-IN-1 (compound 17) is a potent, orally active, and highly selective inhibitor of cholesterol 24-hydroxylase (CH24H or CYP46A1) with IC50 of 8.5 nM that can cross blood-brain barrier [1].
T30161	EN3356	AS N001,ASN-001	P450
	EN3356 is an orally available and selective inhibitor of steroidal 17-alpha-hydroxylase/C17,20 cleavage enzyme (CYP17A1 or CYP17), a non-steroidal cleavage enzyme-selective compound with potential anti-androgenic and ant...		P450
T64393	6-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-1H-pyridine-3,4-dicarbonitrile		Others
	6-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-1H-pyridine-3,4-dicarbonitrile is a biologically active compound, which is utilize...		Others
T14083	Abaperidone		Dopamine Receptor , 5-HT Receptor
	Abaperidone is a potent 5-HT2A receptor and dopamine D2 receptor antagonist with an IC50 of 6.2 for 5-HT2A receptors and 17 nM for dopamine D2 receptors.Abaperidone is a potentially atypical anti-psychotropic compound th...		Dopamine Receptor , 5-HT Receptor
T3142	Drostanolone Propionate		Others
	Dromostanolone propionate (Drostanolone propionate) is a compound that has antitumor activity against breast carcinoma [1]. Dromostanolone propionate inhibits the uptake of oestradiol-17 by the tumor without apparent eff...		Others
T11027	DHODH-IN-4		Dehydrogenase
	DHODH-IN-4 is a human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) inhibitor. The IC50 values of PfDHODH and HsDHODH are 4 μM and 0.18 μM, respectively. DHODH-IN-4 has antimalarial activity.		Dehydrogenase
T20037	C.I. Direct Black 17	Azine Fast Black D,CERN prima 17,Telon Fast Black PE,Diazol Black SD
	C.I. Direct Black 17 is a compound of dye.
T36525	IL-17 modulator 1 disodium
	IL-17 Modulator 1 (disodium) is a potent, orally active compound, known for its high efficacy in modulating IL-17. This compound is extensively utilized for researching various diseases such as psoriasis, ankylosing spon...
T60436	Tubulin inhibitor 17
	Tubulin inhibitor 17 (Compound 3b) is an inhibitor of tubulin polymerization (IC50 = 12.38 µM). Tubulin inhibitor 17 exhibits anticancer activities as well as induces cell apoptosis[1].
T40127	IL-17 modulator 3
	IL-17 modulator 3 (US20200247785A1) is a chemical compound that acts as an IL-17 modulator. It has potential applications in researching inflammation, cancer, and autoimmune diseases.
T60598	Thunbergol
	Thunbergol (Isocembrol) (Compound 17) is a potent inhibitor of TNF-α (IC 50 = 7.2 μM) [1].